Exon Array Analyzer: a web interface for Affymetrix exon array analysis
نویسندگان
چکیده
منابع مشابه
Alternative Splicing Detection Algorithms for Affymetrix Exon Array Data
Generating a variety of transcripts from a single gene is common in many organisms. This process, called alternative splicing, can be found in all classes of eukaryotes. In lower eukaryotes only a small fraction of genes undergoes alternative splicing, while in higher eukaryotes nearly all genes are alternatively spliced[1]. The function of this process is to increase the protein diversity [2]....
متن کاملExon Array Background Correction
MM probes provide controls similar in sequence and location which are useful in removing bias; this takes one probe per informative probe. Because the MM probes hybridize to the perfect match (PM) target, when MM intensities are subtracted from PM intensities the PM response to true target slightly reduced. BGP probes provide a rough estimate of background based on coarsely modeled sequence, wi...
متن کاملX:Map: annotation and visualization of genome structure for Affymetrix exon array analysis
Affymetrix exon arrays aim to target every known and predicted exon in the human, mouse or rat genomes, and have reporters that extend beyond protein coding regions to other areas of the transcribed genome. This combination of increased coverage and precision is important because a substantial proportion of protein coding genes are predicted to be alternatively spliced, and because many non-cod...
متن کاملAnalysis of Affymetrix Exon Arrays
Exon arrays enable the monitoring of expression on a more fine-grained level than conventional 3' arrays. By targeting single exons alternative splicing events can be detected. However, the increased amount of data resulting from the denser coverage of the transcribed regions gives rise to new challenges in data analysis compared to 3' arrays. One must carefully decide which probes are consider...
متن کاملNoncoder: a web interface for exon array-based detection of long non-coding RNAs
Due to recent technical developments, a high number of long non-coding RNAs (lncRNAs) have been discovered in mammals. Although it has been shown that lncRNAs are regulated differently among tissues and disease statuses, functions of these transcripts are still unknown in most cases. GeneChip Exon 1.0 ST Arrays (exon arrays) from Affymetrix, Inc. have been used widely to profile genome-wide exp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bioinformatics
سال: 2009
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btp577